You need to consider that there is a fundamental issue of uncertainty with using 4 Pa as a reference pressure. Just imagine, if there is even a 1 Pa fluctuation, due to so many possible sources that can cause pressure fluctuations as you know, the pressure measurement already has an uncertainty of +/- 25% error. Consider that for almost all airtightness testing standards across the world, the reference pressure for Flow results are either 50 Pa or 75 Pa.